Celiac plexus radiosurgery - an introduction to the method and a practical manual

Area of Science:

• Oncology
• Pain Management
• Radiotherapy

Background:

• Cancer-related celiac plexus damage causes severe pain, often resistant to conventional analgesics.
• High doses of analgesics can lead to toxicity.
• Celiac plexus radioablation (CPR) is an emerging non-invasive treatment option.

Purpose of the Study:

• To provide an overview of CPR.
• To offer a guide for performing CPR and managing patients.
• To share clinical experience with this novel radiotherapy technique.

Main Methods:

• Prospective single-arm clinical trial with 125 patients.
• Administration of a high single dose of 25 Gy to the celiac plexus.
• Utilizing advanced radiotherapy techniques for precise targeting.

Main Results:

• CPR demonstrated validated safety and efficacy in a clinical trial.
• Positive trial outcomes supported CPR's integration into pain management guidelines.
• The study provides practical guidance based on clinical experience.

Conclusions:

• CPR is an effective non-invasive treatment for cancer-related celiac plexus pain.
• The study offers a comprehensive guide for CPR implementation and patient management.
• This resource aims to assist clinicians in adopting this novel radiotherapy approach.