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Published on: September 12, 2014
Self-retained, cryopreserved amniotic membrane for a scleral defect caused by mitomycin C: A case report
Brett Bielory1,2,3,4
1New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Purpose:
To report a case of scleral melting noted within weeks after symblepharon release and pterygium excision with peri-operative adjuvant topical Mitomycin C (MMC) that was salvaged with in-office cryopreserved membrane.
Observations:
A 61-year-old Hispanic gentleman with history of pterygium excision many years prior underwent right nasal pterygium excision and symblepharon release using bare sclera technique followed by topical MMC 0.1 % for a week, 16 years ago. He was noted to have a right nasal scleral thinning. He was successfully treated conservatively with in-office cryopreserved amniotic membrane without further progression of the scleral melting or surgical intervention required.
Conclusions And Importance:
Short-term complication of pterygium excision with adjuvant topical MMC may occur. This case shows that early detection and recognition of the complication can be sight-saving with in-office cryopreserved amniotic membrane.

