Related Experiment Video
Updated: Jun 8, 2025

Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation
Published on: May 2, 2020
A comprehensive update on over the counter artificial tears.
Lilla Simon1, Brian A Murillo, Alfonso L Sabater
1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Artificial tears are crucial for dry eye disease (DED) management. Product composition significantly impacts treatment efficacy and potential ocular damage, guiding clinical choices for DED.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Artificial tears are vital for managing dry eye disease (DED), offering symptomatic relief and improving ocular surface health.
- Pharmaceutical innovation has led to diverse artificial tear formulations and ingredients.
Purpose of the Study:
- To provide an overview of currently available artificial tear products.
- To highlight the importance of product composition in DED management.
Main Methods:
- Review of artificial tear products on the market.
- Analysis of active ingredients, inactive ingredients, preservatives, and formulation.
Main Results:
- Artificial tears vary significantly in their composition.
- Ingredient and formulation specifics influence clinical effectiveness in treating ocular pathology.
- Certain ingredients may cause ocular damage.
Conclusions:
- Clinicians must consider artificial tear composition when selecting treatments for DED.
- Tailoring artificial tear selection to specific DED causes (e.g., evaporative, aqueous-deficient) is essential for optimal outcomes.
More Related Videos
05:00Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
Published on: April 1, 2019
08:04A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
Published on: January 24, 2020
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...