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Mutagenic evaluation of propranolol in somatic and germ cells of mice
Mutation Research
|March 1, 1986
Abstract:
The mutagenic effect of an antihypertensive drug, propranolol, was studied on somatic and germ cells of Swiss albino mice. The induction of a significant increase in the frequency of micronuclei in erythrocytes was observed at higher dose levels, whereas, in germ cells, propranolol failed to induce significant chromosomal aberrations at any dose tested.