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Native mitral valve streptococcal endocarditis presenting as myocardial infarction and diagnosed with multimodality
Joshua Wilcox1,2, Arshan Jimmy Dadrewalla3, Manil Subesinghe4,5
1Guy's and St Thomas' Hospitals NHS Trust, London, UK.
Insights
A man with flu-like symptoms developed chest pain, revealing myocardial infarction and mitral valve endocarditis caused by Streptococcus gordonii. Multimodality imaging confirmed the diagnosis and embolic events.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Infective endocarditis is a serious infection of the heart valves.
- Prompt diagnosis and treatment are crucial to prevent complications such as embolic events and myocardial infarction.
- Multimodality imaging plays a vital role in diagnosing complex cardiovascular conditions.
Observation:
- A 60-year-old male presented with chest pain and flu-like symptoms.
- ECG and cardiac biomarkers indicated myocardial injury, with coronary angiography showing an obstructed artery.
- Blood cultures identified Streptococcus gordonii, and echocardiography revealed a mitral valve lesion.
Findings:
- The patient was diagnosed with embolic infarction secondary to native mitral valve infective endocarditis.
- [18F]Flurodeoxyglucose Positron Emission Tomography CT, cardiac MRI, and brain MRI confirmed myocardial infarction, mitral valve infection, and cerebral embolic phenomena.
- The case highlights Streptococcus gordonii as a causative agent in infective endocarditis leading to embolic complications.
Implications:
- This case underscores the importance of a flexible, evolving diagnostic strategy when faced with complex clinical presentations.
- Multidisciplinary collaboration, particularly within an endocarditis team, is essential for optimal patient management.
- Advanced multimodality imaging techniques are invaluable for achieving diagnostic certainty in infective endocarditis and its sequelae.
Abstract:
A man in his 60s presented to the emergency department with central crushing chest pain on a background of a week's history of flu-like symptoms. An ECG demonstrated ischaemia with blood tests confirming myocardial injury; catheter angiography revealed an obstructed diagonal coronary artery. In addition, blood tests revealed elevated markers of inflammation, blood cultures grew Streptococcus gordonii and transthoracic echocardiography demonstrated a mitral valve lesion. A diagnosis of embolic infarction secondary to native mitral valve infective endocarditis was made. Imaging with [18F]Flurodeoxyglucose Positron Emission Tomography CT, cardiac MRI and brain MRI confirmed myocardial infarction, mitral valve infection and embolic phenomena within the brain, respectively. This case reinforces the need for strategic flexibility when faced with evolving clinical data, the role of multidisciplinary involvement in an endocarditis team and the benefits of multimodality imaging techniques to secure diagnostic certainty.
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