Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

3.1K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.1K
Integration of Synaptic Events01:28

Integration of Synaptic Events

1.4K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability...
1.4K
Neural Circuits01:25

Neural Circuits

1.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parallax error indicates simple cue-anchoring in the head-direction system.

bioRxiv : the preprint server for biology·2026
Same author

The neurobench framework for benchmarking neuromorphic computing algorithms and systems.

Nature communications·2025
Same author

Multi-band oscillations emerge from a simple spiking network.

Chaos (Woodbury, N.Y.)·2023
Same author

C. elegans enteric motor neurons fire synchronized action potentials underlying the defecation motor program.

Nature communications·2022
Same author

Global minimization via classical tunneling assisted by collective force field formation.

Science advances·2021
Same author

Dimensional reduction of emergent spatiotemporal cortical dynamics via a maximum entropy moment closure.

PLoS computational biology·2020
Same journal

Interplay between oxygen redox and interfacial stability of Li-rich positive electrodes in sulfide-based all-solid-state batteries.

Nature communications·2026
Same journal

Breaking dependence on melanisation imparts diversity to a dogmatic invasion strategy of phytopathogenic fungi.

Nature communications·2026
Same journal

Hydroxyl-rich nanocavities on perovskite enable nearly barrierless intramolecular hydrogen transfer for nitrate electroreduction to ammonia.

Nature communications·2026
Same journal

Household mobility responses to weather extremes in Kyrgyzstan.

Nature communications·2026
Same journal

Autonomous Motion Vision with Tri-bulk-heterojunctioned Organic Adaptation Transistor.

Nature communications·2026
Same journal

Tissue-adhesive hydrogel optical fiber for peripheral optogenetic neuromodulation.

Nature communications·2026
See all related articles

Related Experiment Video

Updated: Jun 8, 2025

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.0K

The backpropagation algorithm implemented on spiking neuromorphic hardware.

Alpha Renner1,2, Forrest Sheldon3,4, Anatoly Zlotnik5

  • 1Institute of Neuroinformatics, University of Zurich and ETH Zurich, Zurich, 8057, Switzerland.

Nature Communications
|November 8, 2024
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel spiking backpropagation algorithm for neuromorphic hardware. This on-chip implementation achieves competitive accuracy for machine learning tasks, paving the way for efficient edge computing applications.

More Related Videos

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.3K
Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.4K

Related Experiment Videos

Last Updated: Jun 8, 2025

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.0K
Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.3K
Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.4K

Area of Science:

  • Neuroscience and Artificial Intelligence
  • Neuromorphic Engineering
  • Machine Learning

Background:

  • Natural neural systems inspire advanced machine learning and neuromorphic circuits.
  • Modern deep learning, particularly backpropagation, faces challenges in neurophysiological plausibility and hardware implementation.
  • Existing neuromorphic approaches often struggle to replicate the exact backpropagation algorithm.

Purpose of the Study:

  • To present a neuromorphic, spiking backpropagation algorithm implemented on Intel's Loihi research processor.
  • To demonstrate a proof-of-principle three-layer circuit capable of on-chip learning.
  • To showcase the feasibility of exact backpropagation in a fully on-chip Spiking Neural Network (SNN).

Main Methods:

  • Implementation of a synfire-gated dynamical information coordination and processing algorithm.
  • Deployment on Intel's Loihi neuromorphic research processor.
  • Training and testing on MNIST and Fashion MNIST datasets for digit and clothing item classification.

Main Results:

  • Successful proof-of-principle demonstration of a three-layer spiking neural network learning task.
  • Achieved classification accuracy competitive with off-chip trained SNNs.
  • Demonstrated an energy-delay product suitable for edge computing applications.

Conclusions:

  • This work represents the first fully on-chip, computer-in-the-loop-free implementation of the exact backpropagation algorithm in an SNN.
  • The developed approach enables low-power, low-latency deep learning applications on neuromorphic processors.
  • Highlights a viable path for integrating advanced machine learning with in-memory, massively parallel neuromorphic hardware.