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Related Experiment Videos

Pulseless disease associated with multiple intracranial aneurysms.

T Masuzawa, T Kurokawa, K Oguro

    Neuroradiology
    |January 1, 1986
    PubMed
    Summary

    This case study details a 64-year-old woman with pulseless disease and multiple brain aneurysms. Rupture of a basilar artery aneurysm caused her death, suggesting hemodynamic forces contributed to aneurysm development.

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    Area of Science:

    • Neurology
    • Vascular Neurology
    • Neuroscience

    Background:

    • Pulseless disease (Takayasu arteritis) can affect cerebral arteries.
    • Multiple intracranial aneurysms are a rare but serious complication.
    • Cerebral hemodynamics may influence aneurysm formation.

    Observation:

    • A 64-year-old woman presented with pulseless disease and multiple intracranial aneurysms.
    • Aneurysms were identified in the internal carotid and basilar-vertebral circulations.
    • Autopsy confirmed fatal rupture of a top basilar artery aneurysm.

    Findings:

    • The patient had aneurysms at the left internal carotid-ophthalmic artery, left internal carotid-posterior communicating artery junction, left basilar-anterior inferior cerebellar artery junction, and the top of the basilar artery.

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  • Cerebral angiography and autopsy revealed the extent of the aneurysms.
  • Overloaded intracranial hemodynamic forces are presumed to play a role in aneurysm development.

    • Implications:

    • This case highlights the complex relationship between pulseless disease, intracranial aneurysms, and hemodynamic stress.
    • Understanding these factors is crucial for managing patients with vascular inflammatory conditions.
    • Further research into hemodynamic forces in aneurysm pathogenesis is warranted.