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Updated: Jun 7, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
Published on: November 30, 2022
MaskAppendix: Backbone-Enriched Mask R-CNN Based on Grad-CAM for Automatic Appendix Segmentation
Emre Dandıl1, Betül Tiryaki Baştuğ2, Mehmet Süleyman Yıldırım3
1Department of Computer Engineering, Faculty of Engineering, Bilecik Seyh Edebali University, 11230 Bilecik, Türkiye.
Background:
A leading cause of emergency abdominal surgery, appendicitis is a common condition affecting millions of people worldwide. Automatic and accurate segmentation of the appendix from medical imaging is a challenging task, due to its small size, variability in shape, and proximity to other anatomical structures.
Methods:
In this study, we propose a backbone-enriched Mask R-CNN architecture (MaskAppendix) on the Detectron platform, enhanced with Gradient-weighted Class Activation Mapping (Grad-CAM), for precise appendix segmentation on computed tomography (CT) scans. In the proposed MaskAppendix deep learning model, ResNet101 network is used as the backbone. By integrating Grad-CAM into the MaskAppendix network, our model improves feature localization, allowing it to better capture subtle variations in appendix morphology.
Results:
We conduct extensive experiments on a dataset of abdominal CT scans, demonstrating that our method achieves state-of-the-art performance in appendix segmentation, outperforming traditional segmentation techniques in terms of both accuracy and robustness. In the automatic segmentation of the appendix region in CT slices, a DSC score of 87.17% was achieved with the proposed approach, and the results obtained have the potential to improve clinical diagnostic accuracy.
Conclusions:
This framework provides an effective tool for aiding clinicians in the diagnosis of appendicitis and other related conditions, reducing the potential for diagnostic errors and enhancing clinical workflow efficiency.

