A Retrospective Analysis of Emergency Versus Elective Surgical Outcomes in Colon Cancer Patients: A Single-Center Study
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Roxana Loriana Negruț1,2, Adrian Coțe3, Adrian Marius Maghiar1,3
1Department of Medicine, Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
Abstract:
Introduction: Emergency surgical interventions for colon cancer are often associated with poorer outcomes compared to elective surgeries due to the advanced state of the disease and the urgency of intervention. This retrospective study aimed to evaluate the management of emergency management of colon cancer and to evaluate differences in patient outcomes. Conducted at a single surgical emergency center, the study analyzed 182 cases, focusing on demographics, tumor characteristics, surgical methods and patient outcomes. Material and Methods: A retrospective observational study was conducted, involving 182 cases who underwent surgery for colon cancer in a single surgical emergency center. Data was collected from hospital records, encompassing demographic details, tumor characteristics, surgical intervention detail and outcomes, alongside with inflammatory profiles. Statistical analyses included descriptive statistics and t-tests with standard significance at p < 0.05. Results: The study showed that emergency cases had significantly poorer in-hospital survival rates (75.42%) compared to elective surgeries. Inflammatory markers such as Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio were higher in emergency cases, suggesting heightened systemic stress. Emergency surgery was also associated with a higher incidence of ostomy and postoperative complications. Conclusions: Emergency surgery for colon cancer is linked to more advanced tumors, increased physiological stress and lesser clinical outcomes. Early detection strategies and active targeted screening could reduce the need for emergency interventions. Future research should focus on early diagnosis protocols and enhancing public health strategies to minimize emergency presentations, thereby leading to better outcomes for colon cancer patients.
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