No Difference in Postoperative Recovery Outcomes Between Opioid-Free and Opioid-Sparing Anesthesia Under Multimodal Analgesic Protocol for Video-Assisted Thoracoscopic Surgery: A Propensity Score Matching Cohort Study
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View abstract on PubMed
Summary
This summary is machine-generated.Opioid-free anesthesia (OFA) and opioid-sparing anesthesia (OSA) offer comparable postoperative recovery in video-assisted thoracoscopic surgery (VATS) patients. Both approaches effectively manage pain and recovery under multimodal protocols, with no significant differences in outcomes.
Area Of Science
- Anesthesiology
- Thoracic Surgery
- Pain Management
Background
- Growing concerns regarding opioid-related risks necessitate reduced perioperative opioid use.
- Multimodal analgesic protocols are increasingly employed to mitigate opioid-associated adverse events.
- Video-assisted thoracoscopic surgery (VATS) presents a specific context for evaluating anesthetic strategies.
Purpose Of The Study
- To compare postoperative recovery outcomes between opioid-free anesthesia (OFA) and opioid-sparing anesthesia (OSA).
- To evaluate the efficacy of OFA versus OSA within a multimodal analgesic framework for VATS.
- To assess pain intensity, opioid consumption, and recovery scores in VATS patients.
Main Methods
- Retrospective cohort study of 196 patients undergoing VATS between August 2019 and December 2021.
- Patients received either dexmedetomidine-based OFA or remifentanil-based OSA.
- Postoperative recovery assessed via Quality of Recovery-15 (QoR-15) scores, opioid consumption, pain intensity, and opioid-related complications.
Main Results
- No significant differences in QoR-15 scores at 24 hours postoperatively between OFA and OSA groups.
- Comparable opioid consumption and pain intensity were observed in both anesthetic approaches.
- Incidence of opioid-related adverse events and intraoperative hemodynamic changes (hypotension, bradycardia) did not significantly differ.
Conclusions
- Both OFA and OSA, integrated into a multimodal analgesic protocol, ensure effective postoperative recovery for VATS.
- Neither anesthetic strategy demonstrated superiority in terms of key recovery outcomes.
- The findings support the use of either OFA or OSA in VATS patients receiving multimodal analgesia.
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