Minimally Invasive Tube Surgery (MITS)-A Novel Method in Glaucoma Drainage Device Implantation

Area of Science:

• Ophthalmology
• Surgical Innovation
• Glaucoma Management

Background:

• A novel surgical technique, Minimally Invasive Tube Surgery (MITS), is introduced for eyePlate-300 glaucoma drainage device (GDD) implantation.
• The eyePlate-300's flexibility enables insertion via a smaller conjunctival incision, reducing surgical trauma.

Purpose of the Study:

• To evaluate the efficacy and safety of the MITS technique for glaucoma drainage device implantation.
• To assess outcomes including intraocular pressure (IOP) reduction, medication usage, and complications over 12 months.

Main Methods:

• A retrospective analysis of thirteen eyes undergoing the MITS procedure was conducted.
• Primary outcome: complete success (IOP 5-21 mmHg and off glaucoma drops).
• Secondary outcomes: best-corrected visual acuity (BCVA), complications, and need for further surgery.

Main Results:

• Twelve out of thirteen eyes (92%) achieved a successful IOP reduction.
• Mean pre-operative IOP of 35.69 mmHg decreased to 11.08 mmHg post-operatively (p < 0.001).
• Mean glaucoma medication use decreased from 3.46 to 0.85 drops (p < 0.001), with no significant change in BCVA.

Conclusions:

• The MITS technique allows glaucoma drainage device implantation through a smaller, less invasive incision.
• Preliminary one-year data indicate the MITS procedure is safe and effective for lowering IOP.
• No intraoperative complications or need for subsequent pressure-lowering surgeries were reported.