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Changes in Erythrocytes in 88 Hyperthyroid Cats
Olga Gójska-Zygner1, Grzegorz Kotomski1, Joanna Gajger1
1LABROS Specjalistyczna Przychodnia Weterynaryjna, Św. Bonifacego 92, 02-940 Warsaw, Poland.
Animals : an Open Access Journal From MDPI
|November 9, 2024
Summary
Feline hyperthyroidism can cause changes in red blood cells (RBCs), including erythrocytosis and microcytosis. Studies show a negative correlation between RBC count and mean corpuscular volume (MCV) in affected cats.
Area of Science:
- Veterinary Medicine
- Endocrinology
- Hematology
Background:
- Limited research exists on erythrocyte alterations in feline hyperthyroidism.
- Concurrent diseases and varying analyzers contribute to study discrepancies.
Purpose of the Study:
- Analyze red blood cell (RBC) changes in 88 hyperthyroid cats without concurrent diseases.
- Identify associations between RBC changes and factors like thyroxine (T4) concentration, age, and sex.
Main Methods:
- Studied 88 hyperthyroid cats.
- Analyzed red blood cell parameters.
- Assessed correlations with serum T4, age, and sex.
Main Results:
- Observed erythrocytosis (12 cats), anemia (4 cats), macrocytosis (2 cats), and microcytosis (3 cats).
- Microcytosis occurred in cats with erythrocytosis.
- Found a negative correlation between RBC count and mean corpuscular volume (MCV; r = -0.57, p < 0.001).
Conclusions:
- Erythrocytosis may be a response to microcytosis development in hyperthyroid cats.
- The RBC count and MCV correlation may stem from altered hepcidin, erythropoietin, and thyroid-stimulating hormone (TSH) actions.
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