Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Endospores and Sporulation01:20

Endospores and Sporulation

Endospores are specialized, dormant cells primarily formed by Gram-positive bacteria, including Bacillus and Clostridium, enabling survival under extreme environmental conditions. Due to their unique composition and formation process, these structures are highly resistant to physical and chemical insults, such as extreme heat, ultraviolet and ionizing radiation, desiccation, and toxic chemicals. Rare instances of endospore-like structures have also been observed in some Gram-negative bacteria,...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Tetanus01:29

Tetanus

Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A framework for drought monitoring and assessment from a drought propagation perspective under non-stationary environments.

The Science of the total environment·2024
Same author

Diagnostics and omics technologies for the detection and prediction of metabolic dysfunction-associated steatotic liver disease-related malignancies.

Metabolism: clinical and experimental·2024
Same author

Tobacco smoking is associated with sex- and plaque-type specific upregulation of CRLF1 in atherosclerotic lesions.

Atherosclerosis·2024
Same author

RAB37-mediated autophagy guards ovarian homeostasis and function.

Autophagy·2024
Same author

Partial substitution of wheat flour with kiwi starch: Rheology, microstructure changes in dough and the quality properties of bread.

Food chemistry: X·2024
Same author

Effect of bile duct resection on the prognosis of patients with hepatocellular carcinoma combined with extrahepatic bile duct tumor thrombus.

BMC cancer·2024
Same journal

MAN IS A FOOL….

World neurosurgery·2026
Same journal

One-Year Clinical and Imaging Outcomes After Dedicated Sirolimus-Eluting Stenting for Symptomatic Vertebral Artery Origin Stenosis: A Real-World Cohort Study.

World neurosurgery·2026
Same journal

Can Oxygen Induced Vasomotion Be Harnessed in Traumatic Brain Injury? A Narrative Review of the Relationship Between Oxygenation and Intracranial Pressure.

World neurosurgery·2026
Same journal

A grading system based on multiparametric MRI-predicted tumor perfusion, invasiveness and texture (GOLDS-PIT) for surgical difficulty assessment in pituitary macroadenomas: A prospective single-centre cohort study.

World neurosurgery·2026
Same journal

Outcomes and Prognostic Factors After Hematoma Evacuation With or Without Decompressive Craniectomy for Adult Supratentorial Spontaneous Intracerebral Hemorrhage: A Single-Center Retrospective Cohort Study.

World neurosurgery·2026
Same journal

Management Strategies for Multiple Intracranial Aneurysms: A Comparative Systematic Review and Meta-Analysis.

World neurosurgery·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
05:12

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

10.9K

Brainstem Cryptococcoma.

Tian Lan1, Yaming Wang1

  • 1Department of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, Beijing, China.

World Neurosurgery
|November 9, 2024
PubMed
Summary
This summary is machine-generated.

Brainstem cryptococcoma, a rare fungal infection, can mimic other brain lesions. This case highlights unusual imaging features, aiding in diagnosing these rare central nervous system infections.

Keywords:
Brainstem lesionCryptococcal infectionsCryptococcomaMRI

More Related Videos

Zika Virus Infection of Cultured Human Fetal Brain Neural Stem Cells for Immunocytochemical Analysis
10:27

Zika Virus Infection of Cultured Human Fetal Brain Neural Stem Cells for Immunocytochemical Analysis

Published on: February 5, 2018

6.5K
Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection
09:34

Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection

Published on: March 18, 2020

7.7K

Related Experiment Videos

Last Updated: Jun 18, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
05:12

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

10.9K
Zika Virus Infection of Cultured Human Fetal Brain Neural Stem Cells for Immunocytochemical Analysis
10:27

Zika Virus Infection of Cultured Human Fetal Brain Neural Stem Cells for Immunocytochemical Analysis

Published on: February 5, 2018

6.5K
Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection
09:34

Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection

Published on: March 18, 2020

7.7K

Area of Science:

  • Medical Mycology
  • Neuroimaging
  • Infectious Diseases

Background:

  • Cryptococcoma is a focal manifestation of Cryptococcus infection in the central nervous system, typically occurring in the cerebral or cerebellar lobes.
  • Brainstem cryptococcoma is exceptionally rare, with limited reported cases and varied imaging presentations.

Purpose of the Study:

  • To describe a rare case of brainstem cryptococcoma with unique imaging characteristics.
  • To emphasize the diverse imaging spectrum of brainstem cryptococcoma for improved differential diagnosis.

Main Methods:

  • Case presentation of a 37-year-old male with a brainstem occupying lesion.
  • Review of magnetic resonance imaging (MRI) findings.
  • Pathological examination and treatment strategy discussion.

Main Results:

  • The patient presented with an isolated, homogeneously enhanced solid lesion in the brainstem, atypical for cryptococcoma.
  • Initial imaging lacked typical infectious disease indicators, posing a diagnostic challenge.
  • Final diagnosis confirmed brainstem cryptococcoma through pathological examination.

Conclusions:

  • Brainstem cryptococcoma can present with varied and unusual imaging features, including isolated, homogeneously enhanced solid lesions.
  • Recognition of these diverse presentations is crucial for accurate differential diagnosis of brainstem lesions.
  • This case expands the understanding of imaging manifestations for this rare fungal infection.