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Novel Asymmetrical Linear Stapler: Safety Test and Pathological Assessment in a Porcine Model
Yong Chae Jung1, Wen Xue Piao1, Ji-Yeon Kim2
1Department of Thoracic and Cardiovascular Surgery, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, South Korea.
The Journal of Surgical Research
|November 10, 2024
Summary
The novel asymmetrical linear stapler (NALS) provides secure stump closure and is superior to the symmetrical linear stapler (SLS) for accurately evaluating surgical margins in gastrointestinal resections.
Area of Science:
- Surgical Oncology
- Pathology
- Medical Devices
Background:
- Surgical margin involvement impacts cancer patient prognosis.
- Linear staplers are common in lung and gastrointestinal resections.
- Current staplers may hinder accurate pathological margin evaluation.
Purpose of the Study:
- Compare a novel asymmetrical linear stapler (NALS) with a symmetrical linear stapler (SLS).
- Evaluate stump security and pathological margin accuracy in a porcine model.
Main Methods:
- Small bowel resection performed in a porcine model using NALS and SLS (control).
- Assessed hemostasis, stump tightness (burst pressure), and margin-to-staple line distance.
- Pathological evaluation of resection margins.
Main Results:
- Both staplers demonstrated effective hemostasis and stump security up to 3.6 kPa.
- NALS showed a significantly greater distance between the true resection margin and staple line on the specimen side.
- No leakage observed under tested burst pressure.
Conclusions:
- NALS is safe for gastrointestinal resection.
- NALS offers improved accuracy for pathological evaluation of true surgical margins compared to SLS.

