[Mathematical model of interphase cell death]

A model of radiation injury of cells is proposed. It involves a diffusion description of the distribution of elementary lesions among cells during irradiation. It is assumed that the probability of cell death depends on the number of elementary lesions. This probability is described by the model of nonspecific radiation response of cells. The survival function is found for a particular case of the dependence of cell death probability on the number of elementary lesions. The asymptotes of this function are obtained for low and high radiation doses. A qualitative comparison with the experimental data is presented.