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Updated: Jun 7, 2025

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
Published on: September 23, 2022
Genetic predisposition to vaccine-induced immune thrombotic thrombocytopenia
Donald M Arnold1,2, Guillaume Paré3, Ishac Nazy1,2
1Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.
Abstract:
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare prothrombotic disorder with a unique clonality-restricted immunological profile. The study by Petito and Bury et al. provides insight into the role of HLA polymorphisms and an inherent predisposition to VITT. Commentary on: Petito et al. Association of human leucocyte antigen loci with vaccine-induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4-derived peptides and MHC-II. Br J Haematol 2025; 206:290-295.
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