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Transient Osteoporosis of Hip as a Part of "Long COVID-19": A Case Series
Sanjay Agarwala1, Mayank Vijayvargiya1, Avinashdev Upadhyay1
1Department of Orthopaedics, P D Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim (West), Mumbai, Maharashtra, India.
Introduction:
Transient osteoporosis of the hip (TOH) presents with symptoms such as groin pain, discomfort, and the presence of bone edema detected on magnetic resonance imaging (MRI) scans. We have observed an increase in the occurrence of TOH in patients following the COVID-19 pandemic.
Case Report:
In this series, we present four cases of TOH that developed after COVID-19 infection. The average cumulative dose of prednisolone exposure in these cases was 788 mg (range 300-1050 mg). The mean duration between diagnosis and COVID-19 infection was 102 days (range 90-123 days). The average duration from the resolution of symptoms to the initiation of bisphosphonate therapy was 98 days (range 90-120 days).
Conclusion:
Bisphosphonate therapy appears to be an effective pharmacological treatment for TOH, providing rapid pain relief and shortening the disease's natural course. This study demonstrates positive outcomes, including normalized MRI results and no progression to avascular necrosis, suggesting bisphosphonates as a promising management option for TOH patients.
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