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A one health roadmap towards understanding and mitigating emerging Fungal Antimicrobial Resistance: fAMR

Matthew C Fisher1, Fiona Burnett2, Clare Chandler3

  • 1MRC Centre for Global Infectious Disease Outbreak Analysis, Imperial, London, UK.

Npj Antimicrobials and Resistance
|November 11, 2024
PubMed

Insights

Fungal antimicrobial resistance (fAMR) threatens health and food security. This roadmap outlines actions to mitigate fAMR risks, emphasizing the need for greater understanding of antifungal impacts.

Area of Science:

  • Mycology
  • Antimicrobial Resistance
  • One Health

Background:

  • Fungal antimicrobial resistance (fAMR) poses a significant and growing threat to human health, animal health, and global food security.
  • The increasing reliance on antifungal agents necessitates a comprehensive understanding of their ecological and health impacts.

Purpose of the Study:

  • To present a roadmap of inter-related actions to mitigate the risks associated with fAMR.
  • To highlight the critical need for enhanced understanding of the one-health consequences of antifungal chemical use.

Main Methods:

  • This study outlines a strategic roadmap.
  • It synthesizes current knowledge and identifies key areas for action.

Main Results:

  • The roadmap details actionable steps to combat fAMR.
  • It emphasizes the interconnectedness of human, animal, and environmental health in addressing this challenge.

Conclusions:

  • Mitigating fAMR requires a coordinated, multi-faceted approach.
  • Sustainable management of fungal diseases depends on scaling our understanding of antifungal impacts in line with escalating usage.
Keywords:
Antimicrobial resistanceFungal infection

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