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[Acute Neisseria subflava endocarditis].

G Guelpa, J R Claivaz, P Delafontaine

    Schweizerische Medizinische Wochenschrift
    |January 25, 1986
    PubMed
    Summary

    A rare case of endocarditis caused by Neisseria subflava in a 50-year-old woman led to neurological complications. Prompt antibiotic treatment with a cephalosporin resulted in a full recovery.

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    Area of Science:

    • Infectious Diseases
    • Cardiology
    • Neurology

    Background:

    • Endocarditis is a serious infection of the heart's inner lining, often affecting heart valves.
    • Prosthetic valves, like the Starr valve in this case, can be susceptible to infection.
    • Neisseria subflava, a bacterium from the upper respiratory tract, is an uncommon cause of endocarditis.

    Observation:

    • A 50-year-old woman presented with acute endocarditis on a mitral Starr valve.
    • The causative agent was identified as Neisseria subflava, a rare pathogen in endocarditis.
    • The patient experienced significant complications, including right hemiplegia.

    Findings:

    • This case highlights the rarity of Neisseria subflava endocarditis, with only nine previously described instances.
    • The patient's susceptibility to moxalactam, a third-generation cephalosporin, allowed for successful medical treatment.
    • Neurological complications, such as hemiplegia, were observed, marking the third reported instance in N. subflava endocarditis.

    Implications:

    • Endocarditis caused by Neisseria subflava and other saprophytic Neisseria species may frequently lead to neurological and systemic embolic events.
    • Early diagnosis and appropriate antibiotic therapy, guided by susceptibility testing, are crucial for managing this rare condition.
    • Further research is warranted to understand the specific mechanisms and risk factors associated with embolic complications in Neisseria endocarditis.

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