A Huge Conjunctival Atypical Fibroxanthoma.

Area of Science:

• Ophthalmology
• Oncology
• Dermatopathology

Background:

• Conjunctival atypical fibroxanthoma (AFX) is a rare mesenchymal tumor.
• AFX typically presents as a benign lesion, but malignant transformation can occur.

Observation:

• A 50-year-old Hispanic male presented with a rapidly growing conjunctival lesion.
• Biopsy confirmed atypical fibroxanthoma with a component of squamous cell carcinoma.
• The tumor exhibited significant intraocular and extraocular muscle extensions.

Findings:

• The conjunctival atypical fibroxanthoma (AFX) demonstrated aggressive growth and invasion.
• Surgical exenteration was necessary due to the tumor's extensive spread.
• The case highlights the potential for aggressive behavior in conjunctival AFX.

Implications:

• This case underscores the importance of vigilant monitoring for conjunctival lesions.
• Aggressive surgical management may be required for advanced AFX.
• Further research into the behavior and treatment of conjunctival AFX is warranted.