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Updated: May 7, 2026

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Cavernous Sinus Thrombosis Associated With Contralateral Pansinusitis: A Case Report.

Daphne Gunness1, Haris Duvnjak2, Simon Morris3

  • 1Ophthalmology, Wrexham Maelor Hospital, Wrexham, GBR.

Cureus
|November 11, 2024
PubMed
Summary

A rare case of orbital cellulitis complicated by cavernous sinus thrombosis was successfully treated with sinus surgery and anticoagulation. This approach resolved the severe venous thrombosis, preventing further complications.

Keywords:
chronic rhino sinusitisfunctional endoscopic sinus surgery (fess)peri-orbital cellulitispre-septal cellulitisseptic cavernous sinus thrombosis

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Area of Science:

  • Ophthalmology
  • Neurology
  • Infectious Diseases

Background:

  • Orbital cellulitis is an infection of the eye socket tissues.
  • Cavernous sinus thrombosis is a rare but life-threatening condition involving blood clots in the cavernous sinus.

Observation:

  • A healthy woman in her 60s presented with periorbital edema, erythema, neck pain, and fever.
  • Initial diagnosis suggested orbital cellulitis with pansinusitis, but symptoms worsened despite antibiotic treatment.

Findings:

  • Imaging revealed extensive thrombosis of the superior ophthalmic vein, cavernous sinus, and jugular vein.
  • Urgent functional endoscopic sinus surgery and long-term anticoagulation were initiated.

Implications:

  • This case highlights the importance of considering vascular complications in severe orbital infections.
  • Successful management involved a multidisciplinary approach combining surgical intervention and anticoagulation therapy.
  • Prompt diagnosis and treatment are crucial for preventing severe morbidity and mortality associated with cavernous sinus thrombosis.