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Long Term Outcomes in Patients With Differences in Sex Development in Lucknow, India
Nibu Dominic1, Vijayalakshmi Bhatia1, Preeti Dabadghao1
1Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Clinical Endocrinology
|November 11, 2024
Summary
Young adults with differences in sex development (DSD) showed stable gender identity and a preference for early genital surgery. Findings highlight a need for improved mental health support for DSD individuals.
Area of Science:
- Endocrinology
- Genetics
- Psychology
Background:
- Outcomes for individuals with differences in sex development (DSD) are influenced by socio-cultural and economic factors.
- Data from India regarding these long-term outcomes are limited.
Purpose of the Study:
- To investigate gender identity, surgical timing preferences, mental health, and quality of life in young adults with DSD in India.
- To provide insights into the psychosocial aspects of DSD management.
Main Methods:
- A study involving 31 young adults with DSD was conducted.
- Data collected included gender identity, opinions on genital surgery timing, suicidal ideation, romantic relationships, and Quality of Life (QOL) using the SF36 scale.
Main Results:
- Gender identity was consistent with sex assigned at birth for most participants.
- A majority favored early childhood genital surgery.
- Six patients reported suicide attempts, and 11 expressed fear of sexual activity.
- QOL scores were comparable to controls, but lower mental QOL was associated with a history of teasing and suicidal thoughts.
Conclusions:
- The study observed a notable lack of significant gender dysphoria among young adults with DSD.
- A strong preference for early surgical intervention was evident.
- There is an urgent need for enhanced mental health support services for individuals with DSD.
Keywords:
DSDcongenital adrenal hyperplasiadisorders of sex developmentgenital surgeryquality of lifeMore Related Videos
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