Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.5K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

739
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
739
Thermoregulation01:26

Thermoregulation

906
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
906
Target Cell Response to Hormones01:22

Target Cell Response to Hormones

2.9K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-strategy investigation identifies amentoflavone as a novel D3R antagonist for Parkinson's disease treatment.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026
Same author

ITM2A promotes thyroid cancer differentiation through metabolic reprogramming and enhances PD-L1-dependent T-cell responses.

Clinical and experimental medicine·2026
Same author

Hesperetin and Naringenin promote glucagon-like peptide-1 secretion from L-cell through activation of TGR5 and alleviated type 2 diabetes.

Frontiers in pharmacology·2026
Same author

Aptamer-functionalized Fe<sub>3</sub>O<sub>4</sub>-BR@Hemin nanozyme for the ultrasensitive colorimetric detection toward Staphylococcus aureus.

Talanta·2026
Same author

Targeting TLR4/non-canonical NF-κB pathway by Bushen Bitong recipe enhances BMSCs-based cartilage repair in osteoarthritis.

Biochemistry and biophysics reports·2026
Same author

Transcriptomic analysis of the effects of dietary chitosan on the molting process in Procambarus clarkii.

Developmental and comparative immunology·2026

Related Experiment Video

Updated: Jun 7, 2025

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

771

Physical activity affects dysthyreosis by thyroid hormones sensitivity: a population-based study.

Shu-Yang Zhang1, Xue-Qing Hu2, Cheng Xiang3

  • 1Department of General Surgery, Shaoxing Hospital of Traditional Chinese Medicine [Shaoxing Traditional Chinese Medicine (TCM) Hospital Affiliated to Zhejiang Chinese Medical University], Shaoxing, Zhejiang, China.

Frontiers in Endocrinology
|November 12, 2024
PubMed
Summary

Regular physical activity (PA) is linked to dysthyreosis through thyroid hormone sensitivity. Modulating thyroid hormone sensitivity via PA may help prevent dysthyreosis.

Keywords:
dysthyreosishypothalamic pituitary thyroid axismetabolic equivalent taskphysical activitysensitivitythyroid feedback quantile-based index

More Related Videos

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
04:05

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse

Published on: October 6, 2023

344
Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations
09:50

Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations

Published on: January 25, 2018

6.7K

Related Experiment Videos

Last Updated: Jun 7, 2025

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

771
Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
04:05

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse

Published on: October 6, 2023

344
Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations
09:50

Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations

Published on: January 25, 2018

6.7K

Area of Science:

  • Endocrinology
  • Public Health
  • Exercise Physiology

Background:

  • Physical activity (PA) is crucial for overall health.
  • The specific relationship between PA and dysthyreosis remains unclear.
  • Understanding this link can inform public health strategies.

Purpose of the Study:

  • To investigate the association between physical activity and dysthyreosis.
  • To explore the mediating role of thyroid hormone indices in this relationship.
  • To identify potential pathways for preventing dysthyreosis through PA.

Main Methods:

  • Population-based study using National Health and Nutrition Examination Survey (NHANES) data.
  • Linear regression and path analysis to assess associations and causality.
  • Restricted cubic spline analysis for non-linear relationships.

Main Results:

  • A significant correlation was found between PA total MET and Thyroid-Stimulating Hormone Index (TSHI) and Thyroid Feedback Quantile-Based Index (TFQI).
  • TFQI was significantly correlated with dysthyreosis occurrence (P<0.05).
  • Path analysis indicated that PA total MET influences dysthyreosis via TFQI, with a non-linear relationship observed.

Conclusions:

  • PA is significantly correlated with dysthyreosis, mediated by thyroid hormone sensitivity.
  • Regulating thyroid hormone sensitivity through PA may be a strategy for dysthyreosis prevention.
  • This highlights the importance of PA in maintaining thyroid health.