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Benjamin Svejgaard¹, Søren Bruno Elmgreen¹

¹Neurologisk Afdeling, Aalborg Universitetshospital.

Ugeskrift for Laeger

|November 12, 2024

Summary

Pure alexia, a condition impairing reading due to occipital lobe lesions, was the sole stroke symptom in two patients. Both cases highlight how specific brain damage can isolate reading deficits.

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Area of Science:

Neuropsychology
Neurology
Neuroimaging

Background:

Pure alexia is a rare neurological disorder characterized by the inability to read despite preserved writing and sensorimotor abilities.
It is typically associated with lesions in the occipital lobe, particularly the left hemisphere.

Observation:

Two distinct cases of pure alexia as the sole manifestation of stroke are presented.
Case 1: A 72-year-old previously healthy female.
Case 2: An 80-year-old male with pre-existing conditions including diabetes, ischemic heart disease, and renal insufficiency.

Findings:

Both patients presented with isolated difficulty in reading, without accompanying aphasia or sensorimotor impairments.
Magnetic Resonance Imaging (MRI) scans confirmed lesions in the left occipital lobe and adjacent brain structures in both individuals.

Implications:

These cases underscore the specific neuroanatomical basis of reading and demonstrate that stroke can selectively affect this function.
Understanding these focal lesions aids in diagnosing and managing pure alexia, contributing to knowledge of brain-behavior relationships.

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