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Related Experiment Videos

Josefine Windfeld-Mathiasen1, Henrik Horwitz1,2, Tor Biering-Sørensen3,4

  • 1Klinisk Farmakologisk Afdeling, Københavns Universitetshospital - Bispebjerg og Frederiksberg Hospital.

Ugeskrift for Laeger
|November 12, 2024
PubMed
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Androgenic anabolic steroid (AAS) abuse harms cardiovascular health, causing hypertension, atherosclerosis, and heart dysfunction. More research is needed to manage these serious side effects.

Area of Science:

  • Cardiology
  • Endocrinology
  • Sports Medicine

Background:

  • Androgenic anabolic steroids (AAS) are performance-enhancing drugs with known health risks.
  • Cardiovascular complications are a significant concern among AAS users.

Purpose of the Study:

  • To review the cardiovascular side effects associated with AAS abuse.
  • To highlight the need for further research in this area.

Main Methods:

  • Literature review of studies on AAS abuse and cardiovascular outcomes.
  • Synthesis of evidence regarding AAS-induced cardiovascular risk factors and diseases.

Main Results:

  • AAS abuse is linked to hypertension and dyslipidemia.
  • It is associated with coronary atherosclerosis and a pro-coagulative state, increasing thromboembolic risk.

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  • AAS use can cause left ventricular hypertrophy, dysfunction, and potentially heart failure.

    • Conclusions:

    • AAS abuse poses significant cardiovascular risks, including structural heart changes and thrombotic events.
    • Current evidence is limited, necessitating further investigation for effective patient management and treatment strategies.