[Tuberculoid lymph node reaction in malignant melanoma]

We report on epitheloid cell reactions, forming small and large nodules within the primarily affected regional lymph nodes in malignant melanoma. The importance of such granulomas for the interpretation of lymphoscintigraphic findings is pointed out. We discuss the histogenesis and different patterns of these tumor-specific reactions. In addition, the question whether these granulomas are the result of an enhanced immunologic tumor surveillance will be under discussion.