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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Related Experiment Video

Updated: Jun 7, 2025

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
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[Plaque characterization and individualized risk assessment].

J M Brendel1,2, K Nikolaou1, B Foldyna3

  • 1Institut für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Tübingen, Tübingen, Deutschland.

Radiologie (Heidelberg, Germany)
|November 12, 2024
PubMed
Summary
This summary is machine-generated.

Accurate coronary artery disease (CAD) risk assessment uses cardiac CT, including CT-FFR and plaque quantification. The CAD-RADS 2.0 classification aids in prognosis and therapy recommendations for better patient outcomes.

Keywords:
Calcium scoringCoronary stenosisHigh-risk plaquePlaque progressionRisk stratification

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Area of Science:

  • Cardiovascular imaging and diagnostics
  • Radiology and medical imaging
  • Interventional cardiology

Context:

  • Cardiac computed tomography (CT) is standard for coronary artery disease (CAD) risk assessment.
  • Coronary CT angiography (CCTA) and calcium scoring are established diagnostic tools.
  • CAD-RADS classification provides a standardized diagnostic framework.

Purpose:

  • To evaluate the role of advanced cardiac CT techniques in CAD risk stratification.
  • To highlight the prognostic value of CT-FFR and plaque quantification.
  • To emphasize the importance of the CAD-RADS 2.0 classification for clinical decision-making.

Summary:

  • Cardiac CT, including calcium scoring and CCTA, is the standard for CAD risk assessment.
  • Emerging methods like CT-FFR and plaque quantification offer enhanced prognostic information.
  • CT-FFR accurately assesses stenosis hemodynamic significance, while plaque composition predicts event risk.

Impact:

  • Improved individual prognosis through accurate plaque characterization.
  • Guideline compliance for CT-FFR in the USA for evaluating stenoses.
  • Expected clinical integration of quantitative plaque analysis for risk stratification.