Recent advances in two-dimensional materials for drug delivery

Area of Science:

• Biomedical Engineering
• Materials Science
• Nanotechnology

Background:

• Two-dimensional (2D) materials possess large surface areas, active sites, and biocompatibility, making them suitable for drug delivery.
• Graphene, black phosphorus, and transition metal dichalcogenides are among the 2D materials extensively studied for biomedical applications.
• Their properties enable efficient drug loading and controlled release, crucial for advanced therapies.

Purpose of the Study:

• To provide a comprehensive review of 2D materials in drug delivery applications.
• To systematically analyze preparation methods, surface modification strategies, and application domains.
• To identify current challenges and future research directions in this field.

Main Methods:

• Systematic literature review and analysis of recent advances in 2D materials for drug delivery.
• Categorization of different 2D materials based on their properties and applications.
• Evaluation of advantages, drawbacks, and future prospects.

Main Results:

• 2D materials offer versatile platforms for drug loading and delivery, with tunable properties.
• Surface modification strategies enhance drug release mechanisms and combination therapy effects.
• Optimized 2D materials show potential for efficient cancer treatment.

Conclusions:

• 2D materials are promising candidates for next-generation drug delivery systems, particularly in oncology.
• Further research is needed to overcome existing challenges and fully realize their therapeutic potential.
• Continued development in material design and surface functionalization will drive innovation in nanomedicine.