Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

3
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
3
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

7
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
7
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

3
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
3
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

5
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
5
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

3
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
3
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

2
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
2

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systolic anterior motion of an anomalous papillary muscle in obstructive hypertrophic cardiomyopathy.

Cardiology in the young·2026
Same author

New-onset refractory status epilepticus/febrile infection-related epilepsy syndrome centers of excellence: A framework for coordinated care, research, and improved outcomes.

Epilepsia·2026
Same author

Peripherally located type I vestibular hair cells are required for several motor behaviors and stimulus-evoked brainstem neural responses in adult mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Bridging the Gap: A Condensed Fetal Cardiology Curriculum Improves Pediatric Cardiology Fellow Performance and Confidence.

Pediatric cardiology·2026
Same author

Environmental Exposures and Atherosclerotic Risk Factors in Vulnerable Youth: The Example of American Indian/Alaska Native Populations.

Current atherosclerosis reports·2026
Same author

Rare Pediatric Venolymphatic Malformations: Pericardial Cyst Mimickers.

JACC. Case reports·2026

Related Experiment Video

Updated: Jun 7, 2025

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

568

Acute on Chronic Rheumatic Valvulitis.

Natalie K Craik1, Joseph Burns1, Nirica Borges1

  • 1Baylor College of Medicine & Texas Children's Hospital, Houston, Texas, USA.

JACC. Case Reports
|November 13, 2024
PubMed
Summary
This summary is machine-generated.

Rheumatic heart disease can affect children, causing severe mitral valve issues and requiring surgery. Early consideration is vital, even without a clear history of strep throat.

Keywords:
United Stateschild, mechanical valveraresocial determinants of healthsocioeconomic

More Related Videos

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

7.0K
Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
04:30

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

3.3K

Related Experiment Videos

Last Updated: Jun 7, 2025

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

568
An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

7.0K
Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
04:30

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

3.3K

Area of Science:

  • Pediatric Cardiology
  • Valvular Heart Disease
  • Rheumatic Heart Disease

Background:

  • Rheumatic heart disease (RHD) is a significant cause of acquired heart disease globally.
  • It typically follows an episode of acute rheumatic fever, often linked to streptococcal infections.
  • Diagnosis can be challenging in the absence of a clear preceding illness history.

Observation:

  • An 11-year-old male presented with respiratory distress, a holosystolic murmur, and a gallop rhythm.
  • Echocardiography demonstrated significant mitral valve thickening and severe mitral regurgitation.
  • Clinical presentation suggested acute on chronic valvulitis.

Findings:

  • Histopathological examination of the explanted valve was consistent with valvulitis.
  • The case highlights a presentation of RHD in a pediatric patient.
  • Diagnostic delay was noted due to the lack of a reported history of acute rheumatic fever.

Implications:

  • This case emphasizes the need to maintain a high index of suspicion for RHD in pediatric patients with valvular heart disease.
  • It suggests that RHD should be considered even when a history of preceding streptococcal infection or acute rheumatic fever is absent.
  • Prompt diagnosis and management are crucial to prevent further cardiac damage and improve outcomes in affected children.