Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Emma Sønderskov1, Jan Duedal Rölfing2, Thomas Baad-Hansen3

  • 1Ortopædkirurgisk Afdeling, Aarhus Universitetshospital.

Ugeskrift for Laeger
|November 13, 2024
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence, treatment and survival of Malignant Peripheral Nerve Sheath Tumor in the Danish neurofibromatosis type 1 population.

The oncologist·2026
Same author

Early osseointegration of two in-house 3D-printed porous titanium implant designs: an <i>in vivo</i> sheep study.

Frontiers in surgery·2026
Same author

A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2026
Same author

In-house 3D printed porous implants: does strontium-coating enhance osseointegration? An <i>in-vivo</i> study in large animals.

Frontiers in surgery·2026
Same author

High Somatostatin Receptor Expression in Alveolar Soft Part Sarcoma Detected by 68Ga-DOTATOC PET/CT.

Clinical nuclear medicine·2026
Same author

Protrusio Acetabuli in Osteogenesis Imperfecta: A Two-Center Study on Incidence and Associated Factors.

Calcified tissue international·2026
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Hereditary multiple exostoses (HME) is a rare genetic disorder causing bone growths. Management focuses on symptom relief in childhood and screening for cancer in adulthood.

Area of Science:

  • Orthopaedics
  • Genetics
  • Radiology

Background:

  • Hereditary multiple exostoses (HME) is a rare autosomal dominant congenital condition.
  • Characterized by the formation of osteocartilaginous exostoses, primarily at the metaphysis of long bones.

Purpose of the Study:

  • To review the management of hereditary multiple exostoses.
  • To highlight the importance of clinical follow-ups in both pediatric and adult patients.
  • To emphasize the role of MRI in adult HME for detecting malignant transformation.

Main Methods:

  • Literature review focusing on hereditary multiple exostoses management.
  • Analysis of clinical follow-up strategies for different age groups.
  • Evaluation of diagnostic tools, particularly MRI, for malignancy screening.

Related Experiment Videos

Main Results:

  • Surgery is the primary treatment modality for HME due to the absence of medical therapies.
  • Childhood management involves symptom control and surgical removal of symptomatic exostoses.
  • Adult management includes regular MRI scans to monitor for and rule out malignant transformation of exostoses.

Conclusions:

  • Effective management of HME requires tailored approaches for pediatric and adult populations.
  • Long-term orthopedic surveillance is crucial for individuals with HME.
  • MRI plays a vital role in the lifelong care of HME patients by detecting potential malignancies.