Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

2.5K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
2.5K
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

2.0K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists...
2.0K
Preparation and Reactions of Thiols02:33

Preparation and Reactions of Thiols

6.0K
Thiols are prepared using the hydrosulfide anion as a nucleophile in a nucleophilic substitution reaction with alkyl halides. For instance, bromobutane reacts with sodium hydrosulfide to give butanethiol.
6.0K
Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

4.7K
Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
4.7K
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

3.4K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
3.4K
Polymers02:34

Polymers

35.1K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
35.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between iron supplementation during pregnancy and delivery mode on double burden of malnutrition in South Asia: A cross-sectional survey study.

JPEN. Journal of parenteral and enteral nutrition·2026
Same author

Directing chiral induction in hollow helical organic nanotubes.

Organic & biomolecular chemistry·2026
Same author

Design and synthesis of macrocycles with tuneable diameters and helical foldamers with customizable peripheral side chains.

Chemical science·2025
Same author

Nanoconfined Photopolymerization in Self-Assembled Glycerol Monooleate, Hydroxyethyl Acrylate, and Water Suprastructures.

ACS applied materials & interfaces·2025
Same author

Core-Shell Hyperbranched Polymers via Catalytic Ring-Opening Metathesis Polymerization.

Angewandte Chemie (International ed. in English)·2025
Same author

N-Amino Norbornene Imides as Scalable Monomers for Living Ring-Opening Metathesis Polymerization.

ACS macro letters·2025
Same journal

Multitargeted Degradation of Cell Surface Receptors by Modular Glyco-Nanosheets.

ACS macro letters·2026
Same journal

Vinyl Ether Maleic Anhydride Copolymers: Efficient and Reusable Sorbents for Removing Heavy Metals from Water.

ACS macro letters·2026
Same journal

Topology-Preserving Elastic Deformation Augmentation Enables Robust Defect Detection in Data-Scarce Industrial Imagery.

ACS macro letters·2026
Same journal

Flexible Porous Organic Polymers with α,β-Enone-Linkage via AlCl<sub>3</sub>-Catalyzed Horner-Wadsworth-Emmons Polymerization for Pd Recovery.

ACS macro letters·2026
Same journal

Light-Controlled Topology Switching Enables Continuous Modulation of Thermally Induced Phase Behavior in Polymer Solutions.

ACS macro letters·2026
Same journal

Correction to "Light-Induced Transformation from Covalent to Supramolecular Polymer Networks".

ACS macro letters·2026
See all related articles

Related Experiment Video

Updated: Jun 7, 2025

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

10.7K

Catalytic Syntheses of Thiol-End-Functionalized ROMP Polymers.

Ankita Mandal1, Ijaj Ahmed1, Andreas F M Kilbinger1

  • 1Department of Chemistry, University of Fribourg, CH-1700 Fribourg, Switzerland.

ACS Macro Letters
|November 13, 2024
PubMed
Summary
This summary is machine-generated.

Researchers developed a simple method to create thiol-end-functionalized polymers using ring-opening metathesis polymerization (ROMP). This technique offers a more efficient synthesis of these versatile materials for various applications.

More Related Videos

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
08:12

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers

Published on: December 16, 2022

3.2K
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

7.2K

Related Experiment Videos

Last Updated: Jun 7, 2025

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

10.7K
Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
08:12

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers

Published on: December 16, 2022

3.2K
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

7.2K

Area of Science:

  • Polymer Chemistry
  • Materials Science

Background:

  • Thiol-functionalized polymers possess unique chemical properties and reactivity, enabling diverse applications.
  • Ring-opening metathesis polymerization (ROMP) is a key technique for polymer synthesis.

Purpose of the Study:

  • To develop a straightforward synthesis for thiol-end-functionalized ROMP polymers.
  • To utilize efficient catalytic ROMP mechanisms with chain transfer agents.

Main Methods:

  • Synthesis of thiol-end-functionalized polymers via catalytic ROMP.
  • Characterization using Size Exclusion Chromatography (SEC), 1H NMR spectroscopy, and MALDI-ToF mass spectrometry.
  • Verification of thiol group presence via gold nanoparticle surface functionalization.

Main Results:

  • Successful synthesis of a variety of thiol-end-functionalized ROMP polymers.
  • Comprehensive characterization confirming polymer structure and thiol functionality.
  • Demonstration of thiol group reactivity through gold nanoparticle conjugation.

Conclusions:

  • The developed method provides an efficient route to thiol-end-functionalized ROMP polymers.
  • This approach uses less ruthenium compared to conventional living ROMP.
  • The synthesized polymers hold significant potential for materials science and biochemical research.