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Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
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[An imprint in the liver].
Pieter H Sloos1, Jan J J de Vries2, Hendrik A Marsman1,3
1OLVG, afd. Chirurgie, Amsterdam.
Nederlands Tijdschrift Voor Geneeskunde
|November 13, 2024
Summary
A rare case of a liver lesion was found to be a uterine myoma, not a hepatic adenoma. This finding highlights the importance of considering unusual diagnoses in patients with a history of uterine fibroids.
Area of Science:
- Reproductive Endocrinology
- Surgical Pathology
- Hepatobiliary Medicine
Background:
- Uterine myomas (fibroids) are common benign tumors of the uterus.
- Hepatic adenomas are benign liver tumors often associated with oral contraceptive use.
- Symptomatic liver lesions require thorough investigation to determine the underlying cause.
Observation:
- A 35-year-old woman with a history of uterine myomas presented with a symptomatic liver lesion.
- Initial imaging and clinical suspicion pointed towards an atypical hepatic adenoma.
- Surgical exploration was performed to diagnose and manage the liver lesion.
Findings:
- The liver lesion was unexpectedly identified as a uterine myoma.
- The myoma was found to be attached to the thoracic wall.
- This suggests a potential iatrogenic or developmental anomaly related to prior uterine myoma treatment.
Implications:
- This case expands the differential diagnosis for symptomatic liver lesions.
- It underscores the importance of a comprehensive patient history, including prior treatments for gynecological conditions.
- Further investigation may be warranted into the mechanisms of uterine myoma migration or adhesion formation.
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