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Implementation of nutritional care bundle is associated with improved growth in preterm infants born before 32

Jiří Dušek1, Elisabeth Stoltz Sjöström2, Itay Nilsson Zamir3

  • 1Faculty of Health and Social Sciences, University of South Bohemia, Department of Neonatology, České Budějovice Hospital, Czech Republic.

Early Human Development
|November 13, 2024
PubMed

Insights

Implementing a nutritional care bundle improved growth and reduced patent ductus arteriosus (PDA) in very preterm (VPT) infants. This nutritional intervention positively impacted infant development and clinical outcomes.

Area of Science:

  • Neonatal Medicine
  • Pediatric Nutrition
  • Clinical Research

Background:

  • Very preterm (VPT) infants (<32 weeks gestational age) face significant challenges with growth and development.
  • Optimizing nutritional support is critical for improving outcomes in this vulnerable population.

Purpose of the Study:

  • To assess the impact of a nutritional care bundle on growth parameters and morbidity in very preterm infants.
  • To determine if a standardized nutritional approach influences key clinical outcomes.

Main Methods:

  • A comparative study involving 87 very preterm infants born in 2018 (Before group) and 75 born in 2020 (After group).
  • A nutritional care bundle was implemented between the two study periods at a single center.
  • Growth metrics (weight, head circumference z-scores) and incidence of treated patent ductus arteriosus (PDA) were analyzed.

Main Results:

  • Infants in the After group showed significantly less decrease in weight and head circumference z-scores compared to the Before group.
  • Full enteral feeds were achieved earlier in the After group (72.9% by day 14 vs. 51.9%).
  • A significantly lower rate of patent ductus arteriosus requiring treatment was observed in the After group (P < 0.001).

Conclusions:

  • Implementation of a nutritional care bundle is associated with enhanced postnatal growth in very preterm infants.
  • The nutritional care bundle may contribute to a reduction in the incidence of patent ductus arteriosus requiring treatment.
  • This standardized approach shows promise for improving overall clinical outcomes in very preterm neonates.
Abstract

Keywords:
Parenteral nutritionPatent ductus arteriosusPretermWeight change

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