Risk Factors for Intraoperative Instability in Sedated Patients Undergoing Pulmonary Vein Isolation Ablation

Area of Science:

• Cardiology
• Anesthesiology
• Medical Imaging

Background:

• Pulmonary vein isolation (PVI) ablation is a standard treatment for atrial fibrillation.
• Deep sedation with propofol is commonly used during PVI.
• Intraoperative instability can complicate PVI procedures.

Purpose of the Study:

• To identify risk factors associated with patient instability during PVI under deep sedation.
• To determine predictors of propofol dose and bolus requirements.

Main Methods:

• Retrospective analysis of 80 patients undergoing their first PVI ablation.
• Data collected from electronic charts and questionnaires.
• Statistical analysis using regression models to assess associations between patient characteristics, echocardiography findings, and propofol usage.

Main Results:

• Higher total propofol dose was associated with drinking status and body mass index (BMI).
• Increased propofol bolus frequency and volume correlated with younger age and higher BMI.
• Higher total propofol dose was linked to larger left atrial dimensions.

Conclusions:

• Younger age, obesity (higher BMI), and current alcohol consumption are risk factors for patient instability during PVI under deep sedation.
• Physicians should consider these factors to ensure safe sedation practices during PVI ablation.