Intraoperative Conduction Mapping to Reduce Postoperative Atrioventricular Block in Complex Congenital Heart Disease
Edward T O'Leary1, Eric N Feins2, Jocelyn Davee1
1Department of Cardiology, Harvard Medical School, Boston Children's Hospital, Boston, Massachusetts, USA.
Journal of the American College of Cardiology
|November 13, 2024
Summary
Intraoperative His bundle (HB) mapping safely reduces postoperative atrioventricular block requiring pacemaker (AVB/PM) in complex congenital heart disease repair. This technique is particularly beneficial for patients with heterotaxy syndrome and non-L-malposed great arteries.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Medical Device Technology
Background:
- Postoperative atrioventricular block requiring pacemaker (AVB/PM) affects 14-25% of complex congenital heart disease (CHD) biventricular repairs.
- Heterotaxy syndrome increases the risk of AVB/PM in these patients.
Purpose of the Study:
- To evaluate the safety and efficacy of intraoperative His bundle (HB) mapping during complex biventricular CHD repair.
- To determine if HB mapping can reduce the incidence of postoperative AVB/PM.
Main Methods:
- Intraoperative HB mapping using a multielectrode grid catheter was performed in 149 patients undergoing complex CHD biventricular repair (2019-2022).
- A cohort of 201 unmapped patients served as controls.
- The primary outcome measured was postoperative AVB/PM.
Main Results:
- HB was identified in 97% of mapped patients; median mapping time was 6 minutes.
- Postoperative AVB/PM was significantly reduced in mapped patients with heterotaxy (2% vs 16%) and those without L-malposed great arteries (3% vs 11%).
- No intraoperative systemic air embolism occurred during HB mapping.
Conclusions:
- Intraoperative HB mapping is safe and effective in reducing postoperative AVB/PM in specific complex CHD populations.
- Patients with heterotaxy syndrome and non-L-malposed great arteries showed significant benefit.
- Further technological advancements are needed for high-risk subgroups.


