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Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
Published on: July 14, 2023
815
Electroencephalography based delirium screening in acute supratentorial stroke
Gesine Hermann1, Friederike Baumgarte2, Julius Welzel2
1Department of Neurology, Christian-Albrechts-University, University Hospital Schleswig-Holstein, Arnold-Heller-Straße 3, 24105, Kiel, Germany. gesine.hermann@gmx.de.
BMC Neurology
|November 13, 2024
Summary
Single-channel EEG may misdiagnose delirium in stroke patients, especially those with right-sided strokes. Bihemispheric electroencephalogram (EEG) recordings are recommended for accurate delirium detection in stroke survivors.
Area of Science:
- Neuroscience
- Clinical Neurology
- Medical Devices
Background:
- Delirium affects up to 25% of acute stroke patients, with increased risk in older individuals.
- Generalized electroencephalogram (EEG) slowing is indicative of delirium.
- Single-channel EEG devices offer potential for easy delirium detection in intensive care units.
Purpose of the Study:
- To investigate EEG characteristics in stroke patients with and without delirium.
- To compare bihemispheric and single-channel EEG for delirium detection accuracy.
- To analyze the diagnostic performance of a single-channel EEG device (DeltaScan®).
Main Methods:
- Single-channel EEG (DeltaScan®) and routine 21-channel EEG were administered within five days of stroke onset.
- DeltaScan® analyzes right fronto-parietal EEG for polymorphic delta activity (PDA).
- Routine EEG power spectral density (PSD) was analyzed in predefined frequency bands.
Main Results:
- Delirium was diagnosed in 9 of 53 patients (52-90 years).
- DeltaScan® showed 44% sensitivity and 71% specificity for delirium detection.
- Right hemispheric stroke patients had a higher false-positive rate with DeltaScan® (p=0.01); 21-channel EEG revealed significant frontal delta/theta power differences (p<0.05).
Conclusions:
- Bihemispheric EEG recordings are likely superior to unilateral recordings for clinical delirium diagnosis in stroke patients.
- Unilateral EEG-based delirium scoring may yield false-positive results due to stroke-related delta or theta slowing.
