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Features associated with thought disorder in manic patients at 2-4-year follow-up

L S Grossman, M Harrow, J R Sands

    The American Journal of Psychiatry
    |March 1, 1986
    PubMed

    Insights

    Thirty percent of formerly hospitalized manic patients exhibit severe thought disorder years after discharge. This condition is linked to manic behavior, psychosis, and poorer long-term outcomes.

    Area of Science:

    • Psychiatry
    • Clinical Psychology
    • Neuroscience

    Background:

    • Thought disorder is a core symptom of mania.
    • Long-term persistence of thought disorder after acute manic episodes is not well understood.

    Purpose of the Study:

    • To assess the prevalence of thought disorder in formerly hospitalized manic patients.
    • To examine the relationship between persistent thought disorder and clinical variables.

    Main Methods:

    • Follow-up assessment of 47 manic patients 2-4 years post-discharge.
    • Evaluation for severe positive thought disorder.
    • Correlation and regression analyses with clinical variables.

    Main Results:

    • 14 patients (30%) displayed severe positive thought disorder at follow-up.
    • Thought disorder correlated with manic behavior and psychosis.
    • Higher frequency in patients with poor posthospital functioning and chronic illness course.

    Conclusions:

    • Severe thought disorder persists in a significant minority of manic patients.
    • Manic behavior, psychosis, and illness chronicity are associated with persistent thought disorder.

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