Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Electron Microscope Tomography and Single-particle Reconstruction

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

Imaging Studies I: CT and MRI

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

X-ray Imaging

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Contrastive Discrepancy: A label-free metric for deformable image registration supporting testing-time hyperparameter selection.

Medical image analysis·2026

Same author

UniTransAD: Unified Translation Framework for Anomaly Detection in Brain MRI.

IEEE transactions on medical imaging·2026

Same author

Progression of interstitial lung abnormalities and its impact on mortality in patients with lung cancer resection.

Chinese medical journal pulmonary and critical care medicine·2026

Same author

Discriminating nodular pulmonary alveolar proteinosis from lung adenocarcinoma with radiomic model and multimodal model.

Therapeutic advances in respiratory disease·2026

Same author

U<sup>2</sup>AD: Uncertainty-based unsupervised anomaly detection framework for detecting T2 hyperintensity in MRI spinal cord.

Medical image analysis·2026

Same author

A Dual-Stream Mamba With Contrastive Representation for Multimodal Deformable Registration.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

Search research articles

Related Experiment Video

Updated: Jun 7, 2025

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

Published on: May 27, 2008

Joint reconstruction algorithm: combining synchrotron radiation with conventional X-ray computed tomography for

Pengxin Cao, Shiang Zhang, Jun Zhao

|November 14, 2024

Summary

This study introduces a novel method to combine synchrotron radiation (SR) micro-CT and conventional X-ray CT data. This approach overcomes field-of-view limitations, enabling high-resolution imaging of larger objects.

More Related Videos

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

Related Experiment Videos

Last Updated: Jun 7, 2025

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

Published on: May 27, 2008

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

Area of Science:

Medical Imaging
Materials Science
Physics

Background:

Synchrotron radiation (SR) micro-computed tomography (micro-CT) offers high resolution due to monochromaticity and brightness.
Limited field of view (FOV) in SR micro-CT restricts imaging of larger samples, leading to data truncation.
Integrating conventional X-ray CT data can supplement truncated SR data for improved imaging.

Purpose of the Study:

To develop a method for joint reconstruction of SR micro-CT and conventional X-ray CT data.
To overcome the field-of-view limitations of SR micro-CT for larger object imaging.
To enhance imaging quality and utilization efficiency by combining complementary data sources.

Main Methods:

Polynomial transformation for matching image gray levels between SR and conventional X-ray CT data.
Resampling of data to create a joint dataset for reconstruction.
Derivation of noise images to construct an image weight constraint reflecting data quality.
Integration of the image weight constraint with denoisers for enhanced reconstruction.

Main Results:

Successful integration of truncated SR data with conventional X-ray CT data.
Demonstration of improved imaging for larger objects through joint reconstruction.
Validation of the image weight constraint's effectiveness in handling varying data quality.
Enhanced reconstruction quality achieved by combining the proposed method with denoisers.

Conclusions:

The proposed method effectively leverages the strengths of both SR micro-CT and conventional X-ray CT.
This approach facilitates high-resolution imaging of larger-scale samples.
The technique improves the utilization efficiency of SR micro-CT for complex imaging tasks.