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Dementia and Cognitive Decline: A HEALM Approach
Ecler E Jaqua1, Mai-Linh N Tran1, Pedro Alvarez1
1Family Medicine Department, Loma Linda University School of Medicine, Loma Linda, CA, USA (EJ, MLT, PA, MG).
Lifestyle medicine interventions like diet and exercise can significantly reduce dementia risk. This review highlights evidence-based strategies for cognitive health and aging well.
Area of Science:
- Gerontology
- Public Health
- Neurology
Background:
- Dementia and cognitive decline represent escalating global health concerns.
- Lifestyle medicine, encompassing diet, exercise, sleep, social connection, stress management, and substance avoidance, offers potential mitigation strategies.
- Traditional research methods like randomized controlled trials (RCTs) have limitations in assessing long-term lifestyle intervention effects.
Purpose of the Study:
- To evaluate the impact of lifestyle factors on dementia and cognitive decline using the HEALM framework.
- To integrate diverse evidence sources for a comprehensive assessment of lifestyle interventions.
- To inform public health strategies for addressing cognitive aging.
Main Methods:
- Development of the Hierarchies of Evidence Applied to Lifestyle Medicine (HEALM) framework by the American College of Lifestyle Medicine (ACLM) and True Health Initiative (THI).
- Utilizing the Evidence Threshold Pathway Mapping (ETPM) approach to inform the HEALM framework.
- Review and synthesis of evidence on lifestyle interventions' effects on cognitive health.
Main Results:
- Strong evidence supports plant-based nutrition, physical activity, restorative sleep, and avoiding risky substances for cognitive health.
- Social connections show potential in mitigating cognitive decline.
- Findings for stress management remain inconclusive, requiring further investigation.
Conclusions:
- Lifestyle interventions are crucial for promoting cognitive health and managing dementia risk.
- Integrating evidence-based lifestyle strategies into public health initiatives can combat the rising dementia burden.
- Continued research is essential to further elucidate the role of lifestyle in cognitive well-being and aging.
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