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Updated: Jun 7, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
A new tool for estimation of the in vivo distribution of intake radionuclides
Jinghang Wang1, Xin Lin1, Bo Chen1
1Institute of Radiation Medicine, Fudan University, Shanghai 200032, China.
Abstract:
This study developed a more universal tool for estimating the in vivo distribution of intake radionuclides. The biokinetic models and transfer rates for intake radionuclides were cited from the publications of the International Commission on Radiological Protection (ICRP), and the models were transformed into a series of linear differential equations and numerically solved using the Scipy algorithm in Python. The user interfaces for model selection, data input and in vivo distribution calculations were designed using PyQt5. The calculation results of the new tool are completely consistent with those of the data viewer released by the ICRP and are also very similar to other reported values. The new tool allows users to select and change the biokinetic models and transfer rates and display the in vivo distribution of radionuclides in an image format. It is much more user friendly.
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