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Updated: Jun 7, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

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Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and

Jie Luo1, Jeff Ranish1

  • 1Institute for Systems Biology, Seattle, United States.

Elife
|November 14, 2024
PubMed

Keywords:
RNA polymerase IIbiochemistrychemical biologyconformational changecrosslinking mass spectrometrygeneral transcription factorshumanisobaric crosslinkersmolecular biophysicssaccharomyces cerevisiaestructural biologystructural proteomics

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