Related Experiment Video For Breast Neoplasms
Updated: May 5, 2026

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
Published on: October 16, 2010
[Breast cancer: suspicious findings on mastography associated with the histopathological result]
Stephany Priscila Zambrano-Terrazas1, Gloria Patricia Sosa-Bustamante1, Alma Patricia González1
1Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No. 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.
Background:
Breast cancer occupies first place in mortality by neoplasms in women in Mexico; mammography screening (MS) interpreted by BI-RADS (Breast Imaging-Reporting and Data System), allows suspicion of malignancy, which will be confirmed when having the histopathological result (HPR).
Objective:
o evaluate whether suspicious findings for breast cancer in MS are associated with malignant HPR in women aged ≥ 40 years.
Material And Methods:
Observational, analytical, cross-sectional, prolective study. Patients aged ≥ 40 years, with MS with BI-RADS 4a, 4b, 4c and 5, and RHP of sample obtained by Trucut, excisional or ultrasound-guided biopsy were analyzed. Sociodemographic, anthropometric, clinical variables, BI-RADS classification and HPR variables were recorded.
Results:
148 patients were included, median age 53 years; these were stratified into BI-RADS 4a, BI-RADS 4b, BI-RADS 4c and BI-RADS 5. Suspicious findings of malignancy due to MS were associated with HPR. MS BI-RADS 4c, palpable lesion and late menopause were identified as risk factors for malignant HPR; as well as MS BI-RADS 5 and palpable lesión.
Conclusion:
MS with suspicious findings of malignancy is associated with the malignant HPR obtained by biopsy.

