Related Experiment Video
Updated: Jun 7, 2025

09:16
A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
Published on: October 30, 2016
11.2K
mRNA vaccines: A promising platform for safer, more effective next-generation Orthopoxvirus immunization
Xiaonan Han1, Qingrui Huang2, Jinghua Yan2
1CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Cell Host & Microbe
|November 14, 2024
Abstract:
In recent work, Mucker et al.1 demonstrated that mRNA-1769 outperforms modified vaccinia Ankara (MVA), which has been deployed against recent mpox virus (MPXV) outbreaks, in reducing clinical symptoms and controlling viral replication, highlighting its potential as a scalable, safe, and effective next-generation platform for orthopoxvirus vaccination.

