Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

2.9K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor...
2.9K
Somatosensation01:33

Somatosensation

36.4K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.4K
The Cochlea01:13

The Cochlea

44.5K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
44.5K
Association Areas of the Cortex01:21

Association Areas of the Cortex

5.1K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.1K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

413
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
413
Auditory Pathway01:15

Auditory Pathway

4.9K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing fractional CO₂ laser and needling-based modalities in facial acne scar treatment: a comprehensive systematic review and meta-analysis.

Lasers in medical science·2026
Same author

Efficacy of Aldosterone synthase inhibitors in uncontrolled and resistant hypertension: A systematic review and updated meta-analysis with grade assessment.

European journal of internal medicine·2026
Same author

Efficacy and safety of ATRA plus arsenic trioxide versus ATRA plus chemotherapy in newly diagnosed acute promyelocytic leukemia: a grade-assessed systematic review and meta-analysis.

BMC cancer·2026
Same author

Comparative efficacy and safety of remimazolam versus propofol in bronchoscopic procedures: a GRADE-assessed systematic review and meta-analysis.

BMC anesthesiology·2026
Same author

Assessing the educational impact of a new HIV PrEP training module among primary care providers in Southeast Ontario: results from immediate and 3-months post-training evaluation surveys.

AIDS care·2025
Same author

Extraction of gall bladder via umbilical port versus subxiphoid port for laparoscopic cholecystectomy in Pakistan: A systematic review and meta-analysis.

Medicine·2025

Related Experiment Video

Updated: Jun 7, 2025

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging
06:18

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging

Published on: November 21, 2023

715

Representational drift in barrel cortex is receptive field dependent.

Alisha Ahmed1, Bettina Voelcker1, Simon Peron1

  • 1Center for Neural Science, New York University, 4 Washington Pl., Rm. 621, New York, NY 10003, USA.

Current Biology : CB
|November 14, 2024
PubMed
Summary

Even with changing neural activity, stable behavior is possible. A small group of broadly tuned, synchronously active neurons in the somatosensory cortex (vS1) shows higher stability, potentially underpinning consistent object detection.

Keywords:
barrel cortexcortical plasticityrepresentational drift

More Related Videos

Visualization of Cortical Modules in Flattened Mammalian Cortices
08:49

Visualization of Cortical Modules in Flattened Mammalian Cortices

Published on: January 22, 2018

12.8K
Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

70

Related Experiment Videos

Last Updated: Jun 7, 2025

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging
06:18

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging

Published on: November 21, 2023

715
Visualization of Cortical Modules in Flattened Mammalian Cortices
08:49

Visualization of Cortical Modules in Flattened Mammalian Cortices

Published on: January 22, 2018

12.8K
Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

70

Area of Science:

  • Neuroscience
  • Systems Neuroscience
  • Sensory Processing

Background:

  • Cortical neural populations can change activity over time, a phenomenon known as representational drift.
  • Maintaining stable behavior despite this neural drift is a key question in neuroscience.
  • The role of individual neuron stability in preserving behavioral consistency is not well understood.

Purpose of the Study:

  • To investigate how stable behavior is maintained during representational drift in the primary vibrissal somatosensory cortex (vS1).
  • To identify specific neuronal properties associated with stability in whisker touch responses.
  • To understand the dynamics of neuronal functional transitions.

Main Methods:

  • Recording whisker touch responses in layers 2-4 of mouse vS1 over several weeks.
  • Analyzing neuronal activity in mice performing a stable object detection task using two whiskers.
  • Characterizing receptive field tuning, neuronal stability, and pairwise correlations.

Main Results:

  • Individual touch neurons changed their responses over time, despite constant numbers of responsive neurons.
  • Neurons with broader receptive fields exhibited greater stability than narrowly tuned neurons.
  • Transitions to broader tuning were preceded by periods of narrower tuning, and neuronal responsiveness changes were non-random.
  • Broadly tuned neurons in layers 2 and 3 with higher pairwise correlations to other touch neurons were more stable.

Conclusions:

  • A subset of broadly tuned and synchronously active touch neurons demonstrates enhanced stability.
  • These stable neuronal populations may play a critical role in maintaining behavioral stability during representational drift.
  • Understanding neuronal stability is crucial for comprehending how the brain supports consistent behavior.