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Optimising detection of thrombosis in paediatric Staphylococcus aureus bacteraemia: A prospective interventional
Keerthi Anpalagan1, Asha C Bowen2, Leanne Lamborn3
1Wesfarmers Centre of Vaccines and Infectious Disease, The Kids Research Institute Australia, Perth, Australia; School of Medicine, University of Western Australia, Perth, Australia.
Introduction:
Staphylococcus aureus bacteraemia (SAB) is the most common cause of sepsis, contributing to paediatric intensive care unit admission in Australia and New Zealand. While deep venous thrombosis (DVT) has been reported in children with invasive S. aureus infections, the actual frequency and possible effects of thrombosis on disease severity and outcome in paediatric SAB remain unknown. Moreover, guidance regarding imaging for paediatric SAB management are poorly defined.
Methods And Analysis:
We report the protocol for the SNOOPY (Staphylococcus aureus Network; ultrasOund for diagnOsis of endovascular disease in Paediatrics and Youth) study. SNOOPY is a pilot prospective single-arm interventional study that aims to investigate the proportion of children with SAB that have venous thrombosis detected using whole body doppler ultrasound.
