Related Experiment Video
Updated: Jun 7, 2025

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
Published on: August 30, 2013
How does the direction of region of interest selection affect the fractal dimension?
Adem Pekince1, Kader Azlağ Pekince1, Yasin Yasa2
1Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Karabuk University, Karabuk, Turkey.
Objectives:
Introduction Fractal analysis (FA) is a computational method used to quantify the complex trabecular structure of bone. While FA has been widely applied in dentistry, there are challenges in standardizing the technique due to factors such as image resolution, region of interest (ROI) selection, and image processing. This study aimed to investigate the impact of the direction of ROI selection (DROIS) on fractal dimension (FD) calculations.
Methods:
Panoramic radiographs of 226 individuals aged 20-35 years were analyzed. ROIs were selected on the mandibular condyle, angular region, and mental region, and oriented at 0°, 22.5°, 45°, and 67.5° angles. FD was calculated using the box-counting method in ImageJ. The Friedman test and Wilcoxon signed-rank test were used for statistical analysis.
Results:
The FD values differed significantly between the angled ROI groups in all three regions (Friedman test, p < 0.0001). Pairwise comparisons showed significant differences in FD between most ROI orientations, except between 22.5° and 67.5° in the angular region.
Conclusions:
DROIS is an important factor that should be considered in FA studies to ensure reliable and reproducible FD values. Appropriate methodological choices can help account for the influence of DROIS on FD calculations..

