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Streptococcus suis infective endocarditis in patients with Streptococcus suis bacteremia: a retrospective study of

Pongsira Kedsawadevong1, Sirichai Jamnongprasatporn2, Nithima Ratanasit3

  • 1Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

BMC Infectious Diseases
|November 15, 2024
PubMed
Abstract

Insights

Streptococcus suis infective endocarditis (IE) affects nearly 27% of patients with S. suis bacteremia, often causing severe valvular damage. Echocardiography is recommended for early diagnosis and management of this emerging zoonotic disease.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Zoonotic Diseases

Background:

  • Streptococcus suis (S. suis) is a zoonotic pathogen primarily causing meningitis.
  • S. suis infective endocarditis (IE) is an emerging clinical manifestation.
  • Echocardiography may be underutilized in evaluating S. suis bacteremia.

Purpose of the Study:

  • Estimate the prevalence of S. suis IE in patients with S. suis bacteremia.
  • Investigate predictors, echocardiographic features, and clinical outcomes of S. suis IE.
  • Determine the role of echocardiography in S. suis bacteremia.

Main Methods:

  • Single-center retrospective study (Siriraj Hospital, Jan 2007-Sep 2023).
  • Included adult patients with confirmed S. suis bacteremia.
  • Compared IE and non-IE groups; used binary logistic regression for predictors.

Main Results:

  • Prevalence of S. suis IE was 26.8% (95% CI: 17.85-38.05).
  • High rates of perivalvular complications (52.6%) and valvular regurgitation (80.0%).
  • Dyspnea, new murmur, immunologic phenomenon, and heart failure predicted S. suis IE.

Conclusions:

  • S. suis IE has a significant prevalence and leads to severe valvular damage.
  • Echocardiography is strongly suggested for evaluating S. suis bacteremia patients.
  • Consider reclassifying S. suis as a typical organism.
Keywords:
Streptococcus suis bacteremiaStreptococcus suis infective endocarditisOutcomesPrevalence

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