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Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
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Atypical Cogan syndrome: a case report.

K El Bouhmadi1, A Allaoui2, M El Khattab3

  • 1Vertigo Center, Cheikh Khalifa International University HospitalMohammed VI University of Health Sciences, Casablanca, Morocco. Elbkhadija25@gmail.com.

Journal of Medical Case Reports
|November 15, 2024
PubMed
Summary
This summary is machine-generated.

Atypical Cogan syndrome, a rare autoimmune vasculitis, presents with delayed ocular and audiovestibular symptoms. Early diagnosis and treatment, including tuberculosis screening, are crucial for managing this condition and preventing irreversible damage.

Keywords:
Audiovestibular dysfunctionCogan syndromeCorticosteroidsKeratitisTuberculosis

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Area of Science:

  • Rheumatology
  • Ophthalmology
  • Otolaryngology

Background:

  • Cogan syndrome is a rare autoimmune vasculitis affecting the eyes and ears.
  • The atypical form often presents with delayed audiovestibular symptoms and is frequently underdiagnosed.

Observation:

  • A case of a 30-year-old female with recurrent ocular inflammation and later developed Meniere-like symptoms.
  • Ocular biopsies revealed diffuse inflammatory changes; tuberculosis infection was confirmed via positive skin and blood tests.

Findings:

  • The patient was diagnosed with atypical Cogan syndrome after initial tuberculosis treatment failed and audiovestibular symptoms emerged.
  • Long-term corticosteroid therapy resulted in significant improvement of her condition.

Implications:

  • Cogan syndrome requires consideration in cases of unexplained ocular and audiovestibular symptoms, even in atypical presentations.
  • Screening for tuberculosis and other systemic disorders is vital for accurate diagnosis and effective management.
  • Interdisciplinary collaboration is essential for timely and adequate treatment to prevent irreversible lesions.