Related Experiment Video
Updated: Jun 7, 2025

08:12
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
19.0K
Variation Across Organ Procurement Organizations in Deceased-Donor Kidney Offer Notification Practices.
David C Cron1,2, Arnold E Kuk3, Layla Parast4
1Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Clinical Transplantation
|November 15, 2024
Summary
Organ procurement organizations (OPOs) vary widely in how many kidney offers they send initially. Many send more offers than needed, suggesting opportunities to improve kidney allocation efficiency.
Area of Science:
- Transplant Surgery
- Organ Allocation Policy
- Nephrology
Background:
- Understanding kidney offer notification practices is crucial for efficient organ allocation.
- Current practices across organ procurement organizations (OPOs) lack clarity regarding offer distribution early in the kidney allocation timeline.
Purpose of the Study:
- To analyze the distribution of kidney offer notifications across different OPOs.
- To identify variations in initial offer batch sizes and their implications for kidney allocation efficiency.
Main Methods:
- Utilized data from 54,631 deceased-donor kidney match runs between 2017 and 2023.
- Merged Scientific Registry of Transplant Recipients data with offer notification timestamps.
- Quantified the number of offers in the initial notification batch for each OPO.
Main Results:
- Initial kidney offer batches varied significantly across OPOs, ranging from 3 to 746 candidates.
- No correlation was found between initial batch size and kidney placement rank or OPO nonuse rate.
- OPOs with the largest initial batches sent more offers than necessary, while those with the smallest sent fewer than needed.
Conclusions:
- Kidney offer notification practices differ substantially among OPOs.
- Many OPOs extend offers more broadly than required for successful kidney placement.
- Optimizing offer notification strategies could minimize unnecessary communications and enhance overall allocation efficiency.

