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Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
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Bagel sign and how to avoid it in DMEK surgery
Luca Pagano1,2, Fadi Alfaqawi1, Alfredo Borgia1
1St Paul Eye Unit, Liverpool University Hospitals, Liverpool, UK.
European Journal of Ophthalmology
|November 15, 2024
Summary
A new surgical technique for gas injection in Descemet Membrane Endothelial Keratoplasty (DMEK) helps prevent fluid retention. The "bagel sign" aids surgeons in identifying and correcting interface fluid to reduce graft detachment risks.
Area of Science:
- Ophthalmology
- Surgical Techniques
- Corneal Transplantation
Background:
- Descemet Membrane Endothelial Keratoplasty (DMEK) is a corneal transplantation procedure.
- Ensuring proper graft adhesion is crucial for successful DMEK outcomes.
- Interface fluid can lead to graft detachment and post-operative complications.
Purpose of the Study:
- To describe a recommended surgical technique for gas injection during DMEK.
- To highlight intraoperative signs of interface fluid retention.
- To emphasize methods for preventing graft detachment.
Main Methods:
- A two-step gas injection technique using a 1 ml syringe is detailed.
- Initial slow, central gas injection smaller than the graft is performed.
- The gas bubble is enlarged after confirming no interface fluid (absence of the "bagel sign").
Main Results:
- The "bagel sign" serves as an indicator for interface fluid.
- This sign allows for correction of potential issues causing graft detachment.
- The described gas injection technique may prevent fluid retention and reduce detachment risk.
Conclusions:
- Identifying interface fluid retention using the "bagel sign" or iOCT is vital.
- Early detection of fluid can help prevent post-operative complications in DMEK.
- This technique enhances graft adhesion and improves surgical outcomes.

